How to Lose Friends & Alienate People is a 2008 British comedy film based upon Toby Young's 2001 memoir of the same name. The film follows a similar storyline, about his five-year struggle to make it in the United States after employment at Sharps Magazine. The names of the magazine and people Young came into contact with during the time were changed for the film adaptation. The film version (adapted by Peter Straughan) is a highly fictionalized account, and differs greatly from the work upon which it was built.
Directed by Robert B. Weide, it stars Simon Pegg, Kirsten Dunst, Danny Huston, Gillian Anderson, Megan Fox and Jeff Bridges, alongside Max Minghella and Margo Stilley. How to Lose Friends & Alienate People was released simultaneously in the United Kingdom (by Paramount Pictures) and the United States (by Metro-Goldwyn-Mayer) on 3 October 2008.