The Wilderness Trail was 1919 American silent Western film directed by Edward J. Le Saint and starring Tom Mix and Colleen Moore. It was one of the first of two films that featured Mix and Moore. The Wilderness Trail is based on the 1913 Western novel of the same name by Francis William Sullivan and was adapted for the screen by Charles Kenyon.
No prints of The Wilderness Trail are known to exist and the film is now presumed lost.