Michele Lee (born June 24, 1942) is an American actress, singer, dancer, producer and director. She is known for her role as Karen Cooper Fairgate MacKenzie on the 1980s prime-time soap opera Knots Landing (1979–93), for which she was nominated for a 1982 Emmy Award and won the Soap Opera Digest Award for Best Actress in 1988, 1991 and 1992. She was the only performer to appear in all 344 episodes of the series.
Lee began her career on Broadway in Vintage 60 (1960) and How to Succeed in Business Without Really Trying (1961). She made her movie debut in the film version of the latter in 1967. Her other film appearances include the Disney film The Love Bug (1968), The Comic (1969) and Along Came Polly (2004). She was nominated for the Tony Award for Best Actress in a Musical in 1974 for Seesaw, and for the Tony Award for Best Featured Actress in a Play in 2001 for The Tale of the Allergist's Wife. She also played the title role in the 1998 TV film Scandalous Me: The Jacqueline Susann Story, and Madame Morrible in the Broadway musical Wicked in 2015.